You may feel anxious, fatigued, depressed, and even suicidal. Once the drug wears off this high becomes an exhausted and painful low, known as a comedown or crash. Your body temperature, heart rate, and blood pressure will likely increase, and your appetite and need for sleep will fade. Within seconds to minutes it reaches the brain and triggers a surge of dopamine and a rush of pleasure, followed by a high that can last for several hours.ĭuring this period of time, you may feel invincible, heightened, confident, and secure. The drug is absorbed and enters the bloodstream through the veins of the rectum. The effects and side-effects of meth use are largely unchanged whether the drug is absorbed through the veins, the lungs, or the rectum. What Happens To The Body When You Plug Meth?
But significant risks, including addiction and overdose, still remain at play. Taking methamphetamine by way of the rectum has been promoted by harm reduction organizations as a less risky option for recreational drug use.